Interventional Cardiology

The Interventional Cardiology Unit of Ospedale San Raffaele is directed by Dr. Antonio Colombo for the past 15 years and is a leading center in Europe and in the world for treatment of coronary and structural heart disease. Dr. Antonio Colombo has been recognized one of “The most influential scientific minds” by the agency Thomas Reuters in the year 2014.

Areas of expertise span from complex coronary interventions including treatment of coronary total occlusions, usage of bioresorbable scaffolds and treatment of multivessel coronary artery disease including left main stenosis. In the field of structural heart disease the Interventional Department of San Raffaele Hospital has a very large experience in TAVI/TAVR, in MitraClip and in the treatment of a number of structural pathologies. This activity is actively integrated with the Cardiac Surgery Department performing over 1000 open-heart procedures each year.

Main conditions treated

  • Multivessel coronary artery disease
  • Chronic total occlusions
  • Left main coronary stenosis including complex distal bifurcations
  • Transcatheter implantation of aortic valves (TAVI/TAVR)
  • MitraClip
  • Occlusion of Patent Foramen Ovale, Atrial and Ventricular septal defects
  • Occlusion of Left Atrial Appendix
  • Occlusion of paravalvular leaks
  • Carotid Interventions
  • Peripheral Interventions


The research activities of the Interventional Cardiology Unit of Ospedale San Raffaele are and have been published in all major Cardiology Journals. The Department participated and is actively involved in a number of First in Man studies leading to approval of different new devices in addition to taking part in trials under the auspices of the Federal and Drug Administration of USA.



State of the art equipment is available with particular emphasis to imaging. Intravascular ultrasound, optical coherence tomography, high-resolution multislice cardiac scans, cardiac magnetic resonance and new generation cardiac catheterization laboratories are some of the most important equipment available in San Raffaele Hospital. In addition the Interventional Cardiology Unit has all new generation cardiac stents including various bioresorbable scaffolds.


Antonio Colombo is the Director of Interventional Cardiology Unit then there are four Senior Operators, one Senior Doctor in charge of in-patients beds, four Junior Interventionists including two Fellows part of the Master Program in Interventional Cardiology run with University San Raffaele Vita-Salute. There is one physician who is the Director of Clinical Research assisted by two PhD as Research Coordinators.